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2023

2023

Alexandra P M de Koning-Backus, Jessica C Kiefte-de Jong, Jeroen G J van Rooij, Amd-Life Team, André G Uitterlinden, Trudy G Voortman, Magda A Meester-Smoor, Caroline C W Klaver    Lifestyle Intervention Randomized Controlled Trial for Age-Related Macular Degeneration (AMD-Life): Study Design DOI: 10.3390/nu15030602
Audrey Cougnard-Gregoire, Bénédicte M J Merle, Tariq Aslam, Johanna M Seddon, Isabelle Aknin, Caroline C W Klaver, Gerhard Garhöfer, Alfredo Garcia Layana, Angelo Maria Minnella, Rufino Silva, Cécile DelcourtBlue Light Exposure: Ocular Hazards and Prevention-A Narrative Review DOI: 10.1007/s40123-023-00675-3
Eric F Thee, İlhan E Acar, Johanna M Colijn, Magda A Meester-Smoor, Timo Verzijden, Sara J Baart, Mohamed A Jarboui, Sascha Fauser, Carel B Hoyng, Marius Ueffing, Anneke I den Hollander, Caroline C W Klaver; European Eye Epidemiology Consortium and EYE-RISK ProjectSystemic Metabolomics in a Framework of Genetics and Lifestyle in Age-Related Macular Degeneration DOI: 10.3390/metabo13060701
Joëlle E Vergroesen, Eric F Thee, Tosca O E de Crom, Jessica C Kiefte-de Jong, Magda A Meester-Smoor, Trudy Voortman, Caroline C W Klaver, Wishal D Ramdas The inflammatory potential of diet is associated with the risk of age-related eye diseasesDOI: 10.1016/j.clnu.2023.10.008
2022

2022

Anneke I den Hollander, Robert F Mullins, Luz D Orozco, Andrew P Voigt, Hsu-Hsin Chen, Tobias Strunz, Felix Grassmann, Jonathan L Haines, Jonas J W Kuiper, Santa J Tumminia, Rando Allikmets, Gregory S Hageman, Dwight Stambolian, Caroline C W Klaver, Jef D Boeke, Hao Chen, Lee Honigberg, Suresh Katti, Kelly A Frazer, Bernhard H F Weber, Michael B Gorin Systems genomics in age-related macular degenerationDOI: 10.1016/j.exer.2022.109248
David A Merle, Merve Sen, Angela Armento, Chloe M Stanton, Eric F Thee, Magda A Meester-Smoor, Markus Kaiser, Simon J Clark, Caroline C W Klaver, Pearse A Keane, Alan F Wright, Michael Ehrmann, Marius Ueffing 10q26 – The enigma in age-related macular degenerationDOI: 10.1016/j.preteyeres.2022.101154
Joëlle E Vergroesen, Eric F Thee, Fariba Ahmadizar, Cornelia M van Duijn, Bruno H Stricker, Maryam Kavousi, Caroline C W Klaver , Wishal D Ramdas Association of Diabetes Medication With Open-Angle Glaucoma, Age-Related Macular Degeneration, and Cataract in the Rotterdam Study DOI: 10.1001/jamaophthalmol.2022.1435
Maria B Grant, Paul S Bernstein, Kathleen Boesze-Battaglia, Emily Chew, Christine A Curcio, M Cristina Kenney, Caroline Klaver, Nancy J Philp, Sheldon Rowan, Janet Sparrow, Richard F Spaide, Allen Taylor Inside out: Relations between the microbiome, nutrition, and eye health DOI: 10.1016/j.exer.2022.109216
Matthias M Mauschitz, Marie-Therese Schmitz, Timo Verzijden, Matthias Schmid, Eric F Thee, Johanna M Colijn, Cécile Delcourt, Audrey Cougnard-Grégoire, Bénédicte M J Merle, Jean-François Korobelnik, Bamini Gopinath, Paul Mitchell, Hisham Elbaz, Alexander K Schuster, Philipp S Wild, Caroline Brandl, Klaus J Stark, Iris M Heid, Felix Günther, Annette Peters, Caroline C W Klaver, Robert P Finger; European Eye Epidemiology (E) ConsortiumPhysical Activity, Incidence, and Progression of Age-Related Macular Degeneration: A Multicohort Study DOI: 10.1016/j.ajo.2021.10.008
Eric F Thee, Johanna M Colijn, Audrey Cougnard-Grégoire, Magda A Meester-Smoor, Timo Verzijden, Carel B Hoyng, Sascha Fauser, Hans-Werner Hense, Rufino Silva, Catherine Creuzot-Garcher, Marius Ueffing, Cécile Delcourt, Anneke I den Hollander, Caroline C W Klaver; European Eye Epidemiology Consortium and EYE-RISK ProjectThe Phenotypic Course of Age-Related Macular Degeneration for ARMS2/HTRA1: The EYE-RISK ConsortiumDOI: 10.1016/j.ophtha.2022.02.026
Anita de Breuk, Yara T E Lechanteur, Galuh Astuti, Jordi Corominas Galbany, Caroline C W Klaver, Carel B Hoyng, Anneke I den Hollander Common and rare variants in patients with early onset drusen maculopathy DOI: 10.1111/cge.14212
2021

2021

Monika Fleckenstein, Tiarnán D L Keenan, Robyn H Guymer, Usha Chakravarthy, Steffen Schmitz-Valckenberg, Caroline C Klaver, Wai T Wong, Emily Y ChewAge-related macular degenerationdoi: 10.1038/s41572-021-00265-2
Valerie Kuan, Alasdair Warwick, Aroon Hingorani, Adnan Tufail, Valentina Cipriani, Stephen Burgess, Reecha Sofat; International AMD Genomics Consortium (IAMDGC);  Caroline C W Klaver, Anneke den Hollander, Bernhard H F WeberAssociation of Smoking, Alcohol Consumption, Blood Pressure, Body Mass Index, and Glycemic Risk Factors With Age-Related Macular Degeneration: A Mendelian Randomization StudyDOI: 10.1001/jamaophthalmol.2021.4601
Anita de Breuk, Ilhan E Acar, Eveline Kersten, Mascha M V A P Schijvenaars, Johanna M Colijn, Lonneke Haer-Wigman, Bjorn Bakker, Sarah de Jong, Magda A Meester-Smoor, Timo Verzijden, Tom O A R Missotten, Jordi Monés, Marc Biarné , Daniel Pauleikhoff, Hans W Hense, Rufino Silva, Sandrina Nunes, Joana B Melo, Sascha Fauser, Carel B Hoyng, Marius Ueffing, Marieke J H Coenen, Caroline C W Klaver, Anneke I den Hollander; EYE-RISK ConsortiumDevelopment of a Genotype Assay for Age-Related Macular Degeneration: The EYE-RISK ConsortiumDOI: 10.1016/j.ophtha.2020.07.037
Anita de Breuk, Yara T E Lechanteur, Thomas J Heesterbeek, Sascha Fauser , Caroline C W Klaver, Carel B Hoyng, Anneke I den Hollander Genetic Risk in Families with Age-Related Macular DegenerationDOI: 10.1016/j.xops.2021.100087
Soufiane Ajana, Audrey Cougnard-Grégoire, Johanna M Colijn, Bénédicte M J Merle, Timo Verzijden, Paulus T V M de Jong, Albert Hofman, Johannes R Vingerling  Boris P Hejblum, Jean-François Korobelnik, Magda A Meester-Smoor, Marius Ueffing, Hélène Jacqmin-Gadda, Caroline C W Klaver, Cécile Delcourt; EYE-RISK ConsortiumPredicting Progression to Advanced Age-Related Macular Degeneration from Clinical, Genetic, and Lifestyle Factors Using Machine Learning DOI: 10.1016/j.ophtha.2020.08.031
Anita de Breuk, Thomas J Heesterbeek, Bjorn Bakker, Timo Verzijden, Yara T E Lechanteur, Caroline C W Klaver, Anneke I den Hollander, Carel B Hoyng  Evaluating the Occurrence of Rare Variants in the Complement Factor H Gene in Patients With Early-Onset Drusen MaculopathyDOI: 10.1001/jamaophthalmol.2021.4102
Johanna M Colijn, Bart Liefers, Nichole Joachim, Timo Verzijden, Magda A Meester-Smoor, Marc Biarnés, Jordi Monés, Paulus T V M de Jong, Johannes R Vingerling, Paul Mitchell, Clara I Sánchez, Jie J Wang, Caroline C W Klaver; EyeNED Reading Center and EYE-RISK ConsortiumEnlargement of Geographic Atrophy From First Diagnosis to End of Life DOI: 10.1001/jamaophthalmol.2021.1407
Alfredo García-Layana, Gerhard Garhöfer, Tariq M Aslam, Rufino Silva, Cécile Delcourt, Caroline C W Klaver, Johanna M Seddon, Angelo M Minnella Exploring Consensus on Preventive Measures and Identification of Patients at Risk of Age-Related Macular Degeneration Using the Delphi ProcessDOI: 10.3390/jcm10225432
Qingyu Chen, Tiarnan D L Keenan, Alexis Allot, Yifan Peng, Elvira Agrón, Amitha Domalpally, Caroline C W Klaver, Daniel T Luttikhuizen, Marcus H Colyer, Catherine A Cukras, Henry E Wiley, M Teresa Magone, Chantal Cousineau-Krieger, Wai T Wong, Yingying Zhu, Emily Y Chew, Zhiyong Lu; AREDS Deep Learning Research GroupMultimodal, multitask, multiattention (M3) deep learning detection of reticular pseudodrusen: Toward automated and accessible classification of age-related macular degenerationDOI: 10.1093/jamia/ocaa302
2020

2020

İlhan E Acar, Laura Lores-Motta, Johanna M Colijn, Magda A Meester-Smoor, Timo Verzijden, Audrey Cougnard-Gregoire , Soufiane Ajana, Benedicte M J Merle, Anita de Breuk, Thomas J Heesterbeek, Erik van den Akker, Mohamed R Daha, Birte Claes, Daniel Pauleikhoff, Hans-Werner Hense, Cornelia M van Duijn, Sascha Fauser, Carel B Hoyng, Cécile Delcourt, Caroline C W Klaver, Tessel E Galesloot, Anneke I den Hollander; EYE-RISK ConsortiumIntegrating Metabolomics, Genomics, and Disease Pathways in Age-Related Macular Degeneration: The EYE-RISK ConsortiumDOI: 10.1016/j.ophtha.2020.06.020
Eric F Thee, Magda A Meester-Smoor, Daniel T Luttikhuizen, Johanna M Colijn, Clair A Enthoven, Annechien E G Haarman, Dimitris Rizopoulos, Caroline C W Klaver; EyeNED Reading CenterPerformance of Classification Systems for Age-Related Macular Degeneration in the Rotterdam StudyDOI: 10.1167/tvst.9.2.26
Johanna M Colijn, Magda Meester-Smoor, Timo Verzijden, Anita de Breuk, Rufino Silva, Benedicte M J Merle, Audrey Cougnard-Grégoire, Carel B Hoyng, Sascha Fauser, Anthonius Coolen, Catherine Creuzot-Garcher, Hans-Werner Hense, Marius Ueffing, Cecile Delcourt, Anneke I den Hollander, Caroline C W Klaver; EYE-RISK ConsortiumGenetic Risk, Lifestyle, and Age-Related Macular Degeneration in Europe: The EYE-RISK ConsortiumDOI: 10.1016/j.ophtha.2020.11.024
Tobias Strunz, Susette Lauwen , Christina Kiel; International AMD Genomics Consortium (IAMDGC);  Gabriëlle H S Buitendijk, Caroline C W Klaver, Anneke den Hollander, Bernhard H F Weber A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related macular degeneration

DOI: 10.1038/s41598-020-58510-9

2019

2019

Colijn JM, den Hollander AI, Demirkan A, Cougnard-Grégoire A, Verzijden T, Kersten E, Meester-Smoor MA, Merle BMJ, Papageorgiou G, Ahmad S, Mulder MT, Costa MA, Benlian P, Bertelsen G, Bron AM, Claes B, Creuzot-Garcher C, Erke MG, Fauser S, Foster PJ, Hammond CJ, Hense HW, Hoyng CB, Khawaja AP, Korobelnik JF, Piermarocchi S, Segato T, Silva R, Souied EH, Williams KM, van Duijn CM, Delcourt C, Klaver CCW; European Eye Epidemiology Consortium; EYE-RISK Consortium.Increased High-Density Lipoprotein Levels Associated with Age-Related Macular Degeneration: Evidence from the EYE-RISK and European Eye Epidemiology Consortia, Ophthalmology. 2019 Mar;126(3):393-406.

DOI: 10.1016/j.ophtha.2018.09.045

 

de Koning-Backus APM, Buitendijk GHS, Kiefte-de Jong JC, Colijn JM, Hofman A, Vingerling JR, Haverkort EB, Franco OH, Klaver CCW.

Intake of Vegetables, Fruit, and Fish is Beneficial for Age-Related Macular

Degeneration,  Am J Ophthalmol. 2019 Feb;198:70-79.

DOI: 10.1016/j.ajo.2018.09.036
Gattoussi S, Buitendijk GHS, Peto T, Leung I, Schmitz-Valckenberg S, Oishi A, Wolf S, Deák G, Delcourt C, Klaver CCW, Korobelnik JF; European Eye Epidemiology (E3) consortium.The European Eye Epidemiology spectral-domain optical coherence tomography classification of macular diseases for epidemiological studies, Acta Ophthalmol. 2019 Jun;97(4):364-371.DOI: 10.1111/aos.13883
Merle BMJ, Colijn JM, Cougnard-Grégoire A, de Koning-Backus APM, Delyfer MN, Kiefte-de Jong JC, Meester-Smoor M, Féart C, Verzijden T, Samieri C, Franco OH, Korobelnik JF, Klaver CCW, Delcourt C; EYE-RISK Consortium.Mediterranean Diet and Incidence of Advanced Age-Related Macular Degeneration: The EYE-RISK Consortium,  Ophthalmology. 2019 Mar;126(3):381-390.DOI: 10.1016/j.ophtha.2018.08.006
2018

2018

Joachim N, Kifley A, Colijn JM, Lee KE, Buitendijk GHS, Klein BEK, Myers C, Meuer SM, Tan AG, Flood V, Schoufour JD, Franco OH, Holliday EG, Attia J, Liew G, Iyengar SK, de Jong PTVM, Hofman A, Vingerling JR, Mitchell P, Klein R, Klaver CCW, Wang JJ.

 

Joint Contribution of Genetic Susceptibility and Modifiable Factors to the Progression of Age-Related Macular Degeneration over 10 years: The Three Continent AMD Consortium Report,  Ophthalmol Retina. 2018 Jul;2(7):684-693.

DOI: 10.1016/j.oret.2017.10.019

 

Mauschitz MM, Bonnemaijer PWM, Diers K, Rauscher FG, Elze T, Engel C, Loeffler M, Colijn JM, Ikram MA, Vingerling JR, Williams KM, Hammond CJ, Creuzot-Garcher C, Bron AM, Silva R, Nunes S, Delcourt C, Cougnard-Grégoire A, Holz FG, Klaver CCW, Breteler MMB, Finger RP; European Eye Epidemiology (E3) Consortium.

 

Systemic and Ocular Determinants of Peripapillary Retinal Nerve Fiber Layer Thickness Measurements in the European Eye Epidemiology (E3) Population, Ophthalmology. 2018 Oct;125(10):1526-1536.DOI: 10.1016/j.ophtha.2018.03.026
Delcourt C, Le Goff M, von Hanno T, Mirshahi A, Khawaja AP, Verhoeven VJM, Hogg RE, Anastosopoulos E, Cachulo ML, Höhn R, Wolfram C, Bron A, Miotto S, Carrière I, Colijn JM, Buitendijk GHS, Evans J, Nitsch D, Founti P, Yip JLY, Pfeiffer N, Creuzot-Garcher C, Silva R, Piermarocchi S, Topouzis F, Bertelsen G, Foster PJ, Fletcher A, Klaver CCW, Korobelnik JF; European Eye Epidemiology Consortium.The Decreasing Prevalence of Nonrefractive Visual Impairment in Older Europeans: A Meta-analysis of Published and Unpublished Data, Ophthalmology. 2018 Aug;125(8):1149-1159.DOI: 10.1016/j.ophtha.2018.02.005
Buitendijk GHS, Schauwvlieghe AME, Vingerling JR, Schlingemann RO, Klaver CCW; comparing Bevacizumab to Ranibizumab in Age-related macular degeneration (BRAMD) Trial Research Group.Antiplatelet and Anticoagulant Drugs Do Not Affect Visual Outcome in Neovascular Age-Related Macular Degeneration in the BRAMD Trial, Am J Ophthalmol. 2018 Mar;187:130-137.DOI: 10.1016/j.ajo.2018.01.003
van Leeuwen EM, Emri E, Merle BMJ, Colijn JM, Kersten E, Cougnard-Gregoire A, Dammeier S, Meester-Smoor M, Pool FM, de Jong EK, Delcourt C, Rodrigez-Bocanegra E, Biarnés M, Luthert PJ, Ueffing M, Klaver CCW, Nogoceke E, den Hollander AI1, Lengyel I.A new perspective on lipid research in age-related macular degeneration, Prog Retin Eye Res. 2018 Nov;67:56-86.DOI: 10.1016/j.preteyeres.2018.04.006
Corominas J, Colijn JM, Geerlings MJ, Pauper M, Bakker B, Amin N, Lores Motta L, Kersten E, Garanto A, Verlouw JAM, van Rooij JGJ, Kraaij R, de Jong PTVM, Hofman A, Vingerling JR, Schick T, Fauser S, de Jong EK, van Duijn CM, Hoyng CB, Klaver CCW, den Hollander AI.Whole-Exome Sequencing in Age-Related Macular Degeneration Identifies Rare Variants in COL8A1, a Component of Bruch’s Membrane, Ophthalmology. 2018 Sep;125(9):1433-1443.DOI: 10.1016/j.ophtha.2018.03.040
Lorés-Motta L, Riaz M, Grunin M, Corominas J, van Asten F, Pauper M, Leenders M, Richardson AJ, Muether P, Cree AJ, Griffiths HL, Pham C, Belanger MC, Meester-Smoor MA, Ali M, Heid IM, Fritsche LG, Chakravarthy U, Gale R, McKibbin M, Inglehearn CF, Schlingemann RO, Omar A, Chen J, Koenekoop RK, Fauser S, Guymer RH, Hoyng CB, de Jong EK, Lotery AJ, Mitchell P, den Hollander AI, Baird PN, Chowers I.Association of Genetic Variants With Response to Anti-Vascular Endothelial Growth Factor Therapy in Age-Related Macular Degeneration, JAMA Ophthalmol. 2018 Aug 1;136(8):875-884.DOI: 10.1001/jamaophthalmol.2018.2019
Mutlu U, Colijn JM, Ikram MA, Bonnemaijer PWM, Licher S, Wolters FJ, Tiemeier H, Koudstaal PJ, Klaver CCW, Ikram MKAssociation of Retinal Neurodegeneration on Optical Coherence Tomography With Dementia: A Population-Based Study, JAMA Neurol. 2018 Oct 1;75(10):1256-1263DOI: 10.1001/jamaneurol.2018.1563
Kersten E, Paun CC, Schellevis RL, Hoyng CB, Delcourt C, Lengyel I, et al.Systemic and ocular fluid compounds as potential biomarkers in age-related macular degeneration, Surv Ophthalmol. 2018;63(1):9-39.

DOI: 10.1016/j.survophthal.2017.05.003

 

2017

2017

Mutlu U, Bonnemaijer PWM, Ikram MA, Colijn JM, Cremers LGM, Buitendijk GHS, Vingerling JR, Niessen WJ, Vernooij MW, Klaver CCW, Ikram MK.Retinal neurodegeneration and brain MRI markers: the Rotterdam Study, Neurobiol Aging. 2017 Dec;60:183-191.DOI: 10.1016/j.neurobiolaging.2017.09.003
Colijn JM, Buitendijk GHS, Prokofyeva E, Alves D, Cachulo ML, Khawaja AP, Cougnard-Gregoire A, Merle BMJ, Korb C, Erke MG, Bron A, Anastasopoulos E, Meester-Smoor MA, Segato T, Piermarocchi S, de Jong PTVM, Vingerling JR, Topouzis F, Creuzot-Garcher C, Bertelsen G, Pfeiffer N, Fletcher AE, Foster PJ, Silva R, Korobelnik JF, Delcourt C, Klaver CCW; EYE-RISK consortium; European Eye Epidemiology (E3) consortium.Prevalence of Age-Related Macular Degeneration in Europe: The Past and the Future, Ophthalmology. 2017 Dec;124(12):1753-1763.DOI: 10.1016/j.ophtha.2017.05.035
Grassmann F, Kiel C, Zimmermann ME, Gorski M, Grassmann V, Stark K; International AMD Genomics Consortium (IAMDGC),  ……, Fritsche LG,……, Buitendijk GHGenetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits, Genome Med. 2017 Mar 27;9(1):29.DOI: 10.1186/s13073-017-0418-0
Joachim N, Colijn JM, Kifley A, Lee KE, Buitendijk GHS, Klein BEK, Myers CE, Meuer SM, Tan AG, Holliday EG, Attia J, Liew G, Iyengar SK, de Jong PTVM, Hofman A, Vingerling JR, Mitchell P, Klaver CCW, Klein R, Wang JJ.Five-year progression of unilateral age-related macular degeneration to bilateral involvement: the Three Continent AMD Consortium report, Br J Ophthalmol. 2017 Sep;101(9):1185-1192.DOI: 10.1136/bjophthalmol-2016-309729
Ghanbari M, Erkeland SJ, Xu L, Colijn JM, Franco OH, Dehghan A, Klaver CCW, Meester-Smoor MA.Genetic variants in microRNAs and their binding sites within gene 3’UTRs associate with susceptibility to age-related macular degeneration, Hum Mutat. 2017 Jul;38(7):827-838.DOI: 10.1002/humu.23226
2016

2016

Buitendijk GH, Hooghart AJ, Brussee C, de Jong PT, Hofman A, Vingerling JR, Klaver CC.Epidemiology of Reticular Pseudodrusen in Age-Related Macular Degeneration: The Rotterdam Study, Invest Ophthalmol Vis Sci. 2016 Oct 1;57(13):5593-5601.DOI: 10.1167/iovs.15-18816
Lee K, Buitendijk GH, Bogunovic H, Springelkamp H, Hofman A, Wahle A, Sonka M, Vingerling JR, Klaver CC, Abràmoff MD.Automated Segmentability Index for Layer Segmentation of Macular SD-OCT Images, Transl Vis Sci Technol. 2016 Apr 5;5(2):14.DOI: 10.1167/tvst.5.2.14
Fritsche LG, Igl W, Bailey JN, Grassmann F, Sengupta S, Bragg-Gresham JL, Burdon KP, Hebbring SJ, Wen C, Gorski M, Kim IK, Cho D, Zack D, Souied E, Scholl HP, Bala E, Lee KE, Hunter DJ, Sardell RJ, Mitchell P, Merriam JE, Cipriani V, Hoffman JD, Schick T, Lechanteur YT, Guymer RH, Johnson MP, Jiang Y, Stanton CM, Buitendijk GH……., Klaver CCA large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants, Nat Genet. 2016 Feb;48(2):134-43.DOI: 10.1038/ng.3448

Delcourt C, Korobelnik JF, Buitendijk GH, Foster PJ, Hammond CJ, Piermarocchi S, Peto T, Jansonius N, Mirshahi A, Hogg RE, Bretillon L, Topouzis F, Deak G, Grauslund J, Broe R, Souied EH, Creuzot-Garcher C, Sahel J, Daien V, Lehtimäki T, Hense HW, Prokofyeva E, Oexle K, Rahi JS, Cumberland PM, Schmitz-Valckenberg S, Fauser S, Bertelsen G, Hoyng C, Bergen A, Silva R, Wolf S, Lotery A, Chakravarthy U, Fletcher A, Klaver CC.

 

Ophthalmic epidemiology in Europe: the “European Eye Epidemiology” (E3) consortium, Eur J Epidemiol. 2016 Feb;31(2):197-210.DOI: 10.1007/s10654-015-0098-2
Schauwvlieghe AM, Dijkman G, Hooymans JM, Verbraak FD, Hoyng CB, Dijkgraaf MG, Peto T, Vingerling JR, Schlingemann RO.Comparing the Effectiveness of Bevacizumab to Ranibizumab in Patients with Exudative Age-Related Macular Degeneration. The BRAMD Study, PLoS One. 2016 May 20;11(5):e0153052.DOI: 10.1371/journal.pone.0153052
Rodrigues IA, Sprinkhuizen SM, Barthelmes D, Blumenkranz M, Cheung G, Haller J, et al.Defining a Minimum Set of Standardized Patient-centered Outcome Measures for Macular Degeneration,  American Journal of Ophthalmology. 2016;168:1-12.DOI: 10.1016/j.ajo.2016.04.012
van de Graaf ES, Despriet DDG, Klaver CCW, Simonsz HJ.Patient-reported utilities in bilateral visual impairment from amblyopia and age-related macular degeneration, BMC Ophthalmol. 2016;16(1):56.DOI: 10.1186/s12886-016-0234-0
2015

2015

Chaker L, Buitendijk GH, Dehghan A, Medici M, Hofman A, Vingerling JR, Franco OH, Klaver CC, Peeters RP.Thyroid function and age-related macular degeneration: a prospective population-based cohort study–the Rotterdam Study, BMC Med. 2015 Apr 23;13:94.DOI: 10.1186/s12916-015-0329-0
Lechanteur YT, van de Camp PL, Smailhodzic D, van de Ven JP, Buitendijk GH, Klaver CC, Groenewoud JM, den Hollander AI, Hoyng CB, Klevering BJ.Association of Smoking and CFH and ARMS2 Risk Variants With Younger Age at Onset of Neovascular Age-Related Macular Degeneration, JAMA Ophthalmol. 2015 May;133(5):533-41.DOI: 10.1001/jamaophthalmol.2015.18
van Grinsven MJ, Buitendijk GH, Brussee C, van Ginneken B, Hoyng CB, Theelen T, Klaver CC, Sánchez CI.Automatic identification of reticular pseudodrusen using multimodal retinal image analysis, Invest Ophthalmol Vis Sci. 2015 Jan 8;56(1):633-9.DOI: 10.1167/iovs.14-15019
Teussink MM, Lee MD, Smith RT, van Huet RA, Klaver CC, Klevering BJ, et al.The effect of light deprivation in patients with Stargardt disease, Am J Ophthalmol. 2015;159(5):964-72 e2.DOI: 10.1016/j.ajo.2015.02.004
Verhoeven VJ, Wong KT, Buitendijk GH, Hofman A, Vingerling JR, Klaver CC.Visual consequences of refractive errors in the general population, Ophthalmology. 2015;122(1):101-9.DOI: 10.1016/j.ophtha.2014.07.030
2014

2014

Buitendijk GH, Amin N, Hofman A, van Duijn CM, Vingerling JR, Klaver CC.Direct-to-consumer personal genome testing for age-related macular degeneration, Invest Ophthalmol Vis Sci. 2014 Aug 21;55(10):6167-74.DOI: 10.1167/iovs.14-15142
Klein R, Myers CE, Buitendijk GH, Rochtchina E, Gao X, de Jong PT, Sivakumaran TA, Burlutsky G, McKean-Cowdin R, Hofman A, Iyengar SK, Lee KE, Stricker BH, Vingerling JR, Mitchell P, Klein BE, Klaver CC, Wang JJ.Lipids, lipid genes, and incident age-related macular degeneration: the three continent age-related macular degeneration consortium, Am J Ophthalmol. 2014 Sep;158(3):513-24.e3.DOI: 10.1016/j.ajo.2014.05.027
Duvvari MR, Paun CC, Buitendijk GH, Saksens NT, Volokhina EB, Ristau T, Schoenmaker-Koller FE, van de Ven JP, Groenewoud JM, van den Heuvel LP, Hofman A, Fauser S, Uitterlinden AG, Klaver CC, Hoyng CB, de Jong EK, den Hollander AI.Analysis of rare variants in the C3 gene in patients with age-related macular degeneration, PLoS One. 2014 Apr 15;9(4):e94165.DOI: 10.1371/journal.pone.0094165
Klein R, Meuer SM, Myers CE, Buitendijk GH, Rochtchina E, Choudhury F, de Jong PT, McKean-Cowdin R, Iyengar SK, Gao X, Lee KE, Vingerling JR, Mitchell P, Klaver CC, Wang JJ, Klein BE.Harmonizing the classification of age-related macular degeneration in the three-continent AMD consortium, Ophthalmic Epidemiol. 2014 Feb;21(1):14-23.DOI: 10.3109/09286586.2013.867512
Wang JJ, Buitendijk GH, Rochtchina E, Lee KE, Klein BE, van Duijn CM, Flood VM, Meuer SM, Attia J, Myers C, Holliday EG, Tan AG, Smith WT, Iyengar SK, de Jong PT, Hofman A, Vingerling JR, Mitchell P, Klein R, Klaver CC.Genetic susceptibility, dietary antioxidants, and long-term incidence of age-related macular degeneration in two populations, Ophthalmology. 2014 Mar;121(3):667-75.DOI: 10.1016/j.ophtha.2013.10.017
van Hagen PM, Baarsma GS, van Bilsen CE, Kuijpers RW, van Laar JA, van der Ent M, van Daele PL, Veeger NJ, Vingerling JR, Missotten TO.A noncontrolled trial of anti-TNF-α chimeric monoclonal antibody (infliximab, Remicade(®)) in exudative age-related macular degeneration, Acta Ophthalmol. 2014 Dec;92(8):e691-2.DOI: 10.1111/aos.12471
2013

2013

Buitendijk GHS, Rochtchina E, Myers C, van Duijn CM, Lee KE, Klein BEK, Meuer SM, de Jong PTVM, Holliday EG, Tan AG, Uitterlinden AG, Sivakumaran TS, Attia J, Hofman A, Mitchell P, Vingerling JR, Iyengar SK, Janssens ACJW, Wang JJ, Klein R, Klaver CCW.Prediction of age-related macular degeneration in the general population: the Three Continent AMD Consortium, Ophthalmology. 2013 Dec;120(12):2644-2655.DOI: 10.1016/j.ophtha.2013.07.053
Zhan X, Larson DE, Wang C, Koboldt DC, Sergeev YV, Fulton RS, Fulton LL, Fronick CC, Branham KE, Bragg-Gresham J, Jun G, Hu Y, Kang HM, Liu D, Othman M, Brooks M, Ratnapriya R, Boleda A, Grassmann F, von Strachwitz C, Olson LM, Buitendijk GH…….,  Klaver CCIdentification of a rare coding variant in complement 3 associated with age-related macular degeneration, Nat Genet. 2013 Nov;45(11):1375-9.DOI: 10.1038/ng.2758
van de Ven JP, Nilsson SC, Tan PL, Buitendijk GH, Ristau T, Mohlin FC, Nabuurs SB, Schoenmaker-Koller FE, Smailhodzic D, Campochiaro PA, Zack DJ, Duvvari MR, Bakker B, Paun CC, Boon CJ, Uitterlinden AG, Liakopoulos S, Klevering BJ, Fauser S, Daha MR, Katsanis N, Klaver CC, Blom AM, Hoyng CB, den Hollander AI.A functional variant in the CFI gene confers a high risk of age-related macular degeneration, Nat Genet. 2013 Jul;45(7):813-7.DOI: 10.1038/ng.2640
Fritsche LG, Chen W, Schu M, Yaspan BL, Yu Y, Thorleifsson G, Zack DJ, Arakawa S, Cipriani V, Ripke S, Igo RP Jr, Buitendijk GH, Sim X, Weeks DE, Guymer RH, Merriam JE, Francis PJ, Hannum G, Agarwal A, Armbrecht AM, Audo I, Aung T, Barile GR, Benchaboune M, Bird AC, Bishop PN, Branham KE, Brooks M, Brucker AJ, Cade WH, Cain MS, Campochiaro PA, Chan CC……., Vingerling JR……., Klaver CC…….; AMD Gene Consortium.Seven new loci associated with age-related macular degeneration, Nat Genet. 2013 Apr;45(4):433-9, 439e1-2.DOI: 10.1038/ng.2578
Holliday EG, Smith AV, Cornes BK, Buitendijk GH, Jensen RA, Sim X, Aspelund T, Aung T, Baird PN, Boerwinkle E, Cheng CY, van Duijn CM, Eiriksdottir G, Gudnason V, Harris T, Hewitt AW, Inouye M, Jonasson F, Klein BE, Launer L, Li X, Liew G, Lumley T, McElduff P, McKnight B, Mitchell P, Psaty BM, Rochtchina E, Rotter JI, Scott RJ, Tay W, Taylor K, Teo YY, Uitterlinden AG, Viswanathan A, Xie S; Wellcome Trust Case Control Consortium 2, Vingerling JR, Klaver CC, Tai ES, Siscovick D, Klein R, Cotch MF, Wong TY, Attia J, Wang JJ.Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis, PLoS One. 2013;8(1):e53830.DOI: 10.1371/journal.pone.0053830

Ferris FL 3rd, Wilkinson CP, Bird A, Chakravarthy U, Chew E, Csaky K, Sadda SR; Beckman Initiative for Macular Research Classification Committee.

 

Clinical classification of age-related macular degeneration, Ophthalmology. 2013 Apr;120(4):844-51.DOI: 10.1016/j.ophtha.2012.10.036
Chakravarthy U, McKay GJ, de Jong PT, Rahu M, Seland J, Soubrane G, Tomazzoli L, Topouzis F, Vingerling JR, Vioque J, Young IS, Sofat R, Hingorani AD, Fletcher AE.ARMS2 increases the risk of early and late age-related macular degeneration in the European Eye Study, Ophthalmology. 2013 Feb;120(2):342-8.DOI: 10.1016/j.ophtha.2012.08.004
Zhan X, Larson DE, Wang C, Koboldt DC, Sergeev YV, Fulton RS, Fulton LL, Fronick CC, Branham KE, Bragg-Gresham J, Jun G, Hu Y, Kang HM, Liu D, Othman M, Brooks M, Ratnapriya R, Boleda A, Grassmann F, Von Strachwitz C, Olson LM, Buitendijk GHS…….,  Klaver CCW…….,Identification of a rare coding variant in complement 3 associated with age-related macular degeneration, Nat Genet. 2013 Nov;45(11):1375-9DOI: 10.1038/ng.2758
Ong BB, Lee N, Lee WP, Pearce E, Sivaprasad S, Klaver CC, et al.Optimisation of an automated drusen-quantifying software for the analysis of drusen distribution in patients with age-related macular degeneration, Eye (Basingstoke). 2013;27(4):554-60.DOI: 10.1038/eye.2012.292
Zhan X, Larson DE, Wang C, Koboldt DC, Sergeev YV, Fulton RS, et al.Identification of a rare coding variant in complement 3 associated with age-related macular degeneration, Nature Genetics. 2013;45(11):1375-9.DOI: 10.1038/ng.2758
2012

2012

Sobrin L, Ripke S, Yu Y, Fagerness J, Bhangale TR, Tan PL, Souied EH, Buitendijk GH, Merriam JE, Richardson AJ, Raychaudhuri S, Reynolds R, Chin KA, Lee AY, Leveziel N, Zack DJ, Campochiaro P, Smith RT, Barile GR, Hogg RE, Chakravarthy U, Behrens TW, Uitterlinden AG, van Duijn CM, Vingerling JR, Brantley MA Jr, Baird PN, Klaver CC, Allikmets R, Katsanis N, Graham RR, Ioannidis JP, Daly MJ, Seddon JM.Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes, Ophthalmology. 2012 Sep;119(9):1874-85. DOI: 10.1016/j.ophtha.2012.03.014
Baas DC, Ho L, Tanck MW, Fritsche LG, Merriam JE, van het Slot R, Koeleman BP, Gorgels TG, van Duijn CM, Uitterlinden AG, de Jong PT, Hofman A, ten Brink JB, Vingerling JR, Klaver CC, Dean M, Weber BH, Allikmets R, Hageman GS, Bergen AA.Multicenter cohort association study of SLC2A1 single nucleotide polymorphisms and age-related macular degeneration,  Mol Vis. 2012;18:657-74.PMCID: PMC3324365
Smailhodzic D, Klaver CCW, Klevering BJ, Boon CJF, Groenewoud JMM, Kirchhof B, et al.Risk alleles in CFH and ARMS2 are independently associated with systemic complement activation in age-related macular degeneration. Ophthalmology. 2012;119(2):339-46.DOI: 10.1016/j.ophtha.2011.07.056
Sofat R, Casas JP, Webster AR, Bird AC, Mann SS, Yates JRW, et al.Complement factor h genetic variant and age-related macular degeneration: Effect size, modifiers and relationship to disease subtype, International Journal of Epidemiology. 2012;41(1):250-62.DOI: 10.1093/ije/dyr204
2011

2011

Yu Y, Bhangale TR, Fagerness J, Ripke S, Thorleifsson G, Tan PL, Souied EH, Richardson AJ, Merriam JE, Buitendijk GH, Reynolds R, Raychaudhuri S, Chin KA, Sobrin L, Evangelou E, Lee PH, Lee AY, Leveziel N, Zack DJ, Campochiaro B, Campochiaro P, Smith RT, Barile GR, Guymer RH……., Vingerling JR, Klaver CC……., Ho L, van Leeuwen RCommon variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration, Hum Mol Genet. 2011 Sep 15;20(18):3699-709.DOI: 10.1093/hmg/ddr270
Witteman JC, van Duijn CM, Uitterlinden AG, Hofman A, de Jong PT, Vingerling JR, Klaver CC.Reducing the genetic risk of age-related macular degeneration with dietary antioxidants, zinc, and ω-3 fatty acids: the Rotterdam study, Arch Ophthalmol. 2011 Jun;129(6):758-66.DOI: 10.1001/archophthalmol.2011.141
McKay GJ, Patterson CC, Chakravarthy U, Dasari S, Klaver CC, Vingerling JR, Ho L, de Jong PT, Fletcher AE, Young IS, Seland JH, Rahu M, Soubrane G, Tomazzoli L, Topouzis F, Vioque J, Hingorani AD, Sofat R, Dean M, Sawitzke J, Seddon JM, Peter I, Webster AR, Moore AT, Yates JR, Cipriani V, Fritsche LG…….,Evidence of association of APOE with age-related macular degeneration: a pooled analysis of 15 studies, Hum Mutat. 2011 Dec;32(12):1407-16.DOI: 10.1002/humu.21577
Wieberdink RG, Ho L, Ikram MK, Koudstaal PJ, Hofman A, de Jong PT, Vingerling JR, Breteler MM.Age-related macular degeneration and the risk of stroke: the Rotterdam study, Stroke. 2011 Aug;42(8):2138-42.DOI: 10.1161/STROKEAHA.111.616359
McKay GJ, Silvestri G, Chakravarthy U, Dasari S, Fritsche LG, Weber BH, Keilhauer CN, Klein ML, Francis PJ, Klaver CC, Vingerling JR, Ho L, De Jong PT, Dean M, Sawitzke J, Baird PN, Guymer RH, Stambolian D, Orlin A, Seddon JM, Peter I, Wright AF, Hayward C, Lotery AJ, Ennis S, Gorin MB, Weeks DE, Kuo CL, Hingorani AD, Sofat R, Cipriani V, Swaroop A, Othman M, Kanda A, Chen W, Abecasis GR, Yates JR, Webster AR, Moore AT, Seland JH, Rahu M, Soubrane G, Tomazzoli L, Topouzis F, Vioque J, Young IS, Fletcher AE, Patterson CC.Variations in apolipoprotein e frequency with age in a pooled analysis of a large group of older people, Am J Epidemiol. 2011 Jun 15;173(12):1357-64.DOI: 10.1093/aje/kwr015
Smith RT, Sohrab MA, Pumariega NM, Mathur K, Haans R, Blonska A, et al.Drusen analysis in a human-machine synergistic framework, Archives of Ophthalmology. 2011;129(1):40-7.DOI: 10.1001/archophthalmol.2010.328
2010

2010

Baas DC, Ho L, Ennis S, Merriam JE, Tanck MW, Uitterlinden AG, de Jong PT, Cree AJ, Griffiths HL, Rivadeneira F, Hofman A, van Duijn C, Smith RT, Barile GR, Gorgels TG, Vingerling JR, Klaver CC, Lotery AJ, Allikmets R, Bergen AA.The complement component 5 gene and age-related macular degeneration, Ophthalmology. 2010 Mar;117(3):500-11.DOI: 10.1016/j.ophtha.2009.08.032
Baas DC, Despriet DD, Gorgels TG, Bergeron-Sawitzke J, Uitterlinden AG, Hofman A, van Duijn CM, Merriam JE, Smith RT, Barile GR, ten Brink JB, Vingerling JR, Klaver CC, Allikmets R, Dean M, Bergen AA.The ERCC6 gene and age-related macular degeneration, PLoS One. 2010 Nov 1;5(11):e13786. DOI: 10.1371/journal.pone.0013786
2009

2009

Ho L, Witteman JC, Rohrer B, Hofman A, de Jong PT, Vingerling JR.Lipoprotein-associated phospholipase A2 and risk of age-related macular degeneration: the Rotterdam Study, Arch Ophthalmol. 2009 Mar;127(3):340-1. DOI: 10.1001/archophthalmol.2009.8
Topouzis F1, Anastasopoulos E, Augood C, Bentham GC, Chakravarthy U, de Jong PT, Rahu M, Seland J, Soubrane G, Tomazzoli L, Vingerling JR, Vioque J, Young IS, Fletcher AE.Association of diabetes with age-related macular degeneration in the EUREYE study, Br J Ophthalmol. 2009 Aug;93(8):1037-41.DOI: 10.1136/bjo.2008.146316
Despriet DD1, van Duijn CM, Oostra BA, Uitterlinden AG, Hofman A, Wright AF, ten Brink JB, Bakker A, de Jong PT, Vingerling JR, Bergen AA, Klaver CC.Complement component C3 and risk of age-related macular degeneration, Ophthalmology. 2009 Mar;116(3):474-480.e2. DOI: 10.1016/j.ophtha.2008.09.055
Allikmets R, Bergen AA, Dean M, Guymer RH, Hageman GS, Klaver CC, Stefansson K, Weber BH; International Age-related Macular Degeneration Genetics Consortium.Geographic Atrophy in Age-Related Macular Degeneration and TLR3, N Engl J Med. 2009 May 21;360(21):2252-4;PMCID: PMC4853941
Allikmets R, Dean M, Hageman GS, Baird PN, Klaver CC, Bergen AA, Weber BH; International AMD Genetics Consortium.The SERPING1 gene and age-related macular degeneration, Lancet. 2009 Sep 12;374(9693):875-6; author reply 876-7.DOI: 10.1016/S0140-6736(09)61618-4
2008

2008

Ho L, Boekhoorn SS, Liana, van Duijn CM, Uitterlinden AG, Hofman A, de Jong PT, Stijnen T, Vingerling JR.Cataract surgery and the risk of aging macula disorder: the rotterdam study, Invest Ophthalmol Vis Sci. 2008 Nov;49(11):4795-800. DOI: 10.1167/iovs.08-2066
Fletcher AE, Bentham GC, Agnew M, Young IS, Augood C, Chakravarthy U, de Jong PT, Rahu M, Seland J, Soubrane G, Tomazzoli L, Topouzis F, Vingerling JR, Vioque J.Sunlight exposure, antioxidants, and age-related macular degeneration, Arch Ophthalmol. 2008 Oct;126(10):1396-403.DOI: 10.1001/archopht.126.10.1396
Boekhoorn SS, Isaacs A, Uitterlinden AG, van Duijn CM, Hofman A, de Jong PT, Vingerling JR.Polymorphisms in the vascular endothelial growth factor gene and risk of age-related macular degeneration: the Rotterdam Study, Ophthalmology. 2008 Nov;115(11):1899-903. DOI: 10.1016/j.ophtha.2008.06.026

Augood C, Chakravarthy U, Young I, Vioque J, de Jong PT, Bentham G, Rahu M, Seland J, Soubrane G, Tomazzoli L, Topouzis F, Vingerling JR, Fletcher AE.

 

Oily fish consumption, dietary docosahexaenoic acid and eicosapentaenoic acid intakes, and associations with neovascular age-related macular degeneration, Am J Clin Nutr. 2008 Aug;88(2):398-406. DOI: 10.1093/ajcn/88.2.398
Boekhoorn SS, Vingerling JR, Hofman A, de Jong PT.Alcohol consumption and risk of aging macula disorder in a general population: the Rotterdam Study, Arch Ophthalmol. 2008 Jun;126(6):834-9.DOI: 10.1001/archopht.126.6.834
Despriet DD, Bergen AA, Merriam JE, Zernant J, Barile GR, Smith RT, Bakker A, de Jong PT, Allikmets R, Klaver CC.Comprehensive analysis of the candidate genes CCL2, CCR2, and TLR4 in age-related macular degeneration, Invest Ophthalmol Vis Sci. 2008 Jan;49(1):364-71.DOI: 10.1167/iovs.07-0656
2007

2007

Chakravarthy U, Augood C, Bentham GC, de Jong PT, Rahu M, Seland J, Soubrane G, Tomazzoli L, Topouzis F, Vingerling JR, Vioque J, Young IS, Fletcher AE.Cigarette smoking and age-related macular degeneration in the EUREYE Study, Ophthalmology. 2007 Jun;114(6):1157-63. DOI: 10.1016/j.ophtha.2006.09.022
Boekhoorn SS, Vingerling JR, Uitterlinden AG, Van Meurs JB, van Duijn CM, Pols HA, Hofman A, de Jong PT.Estrogen receptor alpha gene polymorphisms associated with incident aging macula disorder, Invest Ophthalmol Vis Sci. 2007 Mar;48(3):1012-7. DOI: 10.1167/iovs.06-0577
Despriet DD, Klaver CC, van Duijn CC, Janssens AC.Predictive value of multiple genetic testing for age-related macular degeneration, Arch Ophthalmol. 2007 Sep;125(9):1270-1.DOI: 10.1001/archopht.125.9.1270
Jager MJ, Klaver CCW.Macrophages feel their age in macular degeneration, J Clin Invest. 2007 Nov;117(11):3182-4.DOI: 10.1172/JCI34070
2006

2006

Despriet DD, Klaver CC, Witteman JC, Bergen AA, Kardys I, de Maat MP, Boekhoorn SS, Vingerling JR, Hofman A, Oostra BA, Uitterlinden AG, Stijnen T, van Duijn CM, de Jong PT.Complement factor H polymorphism, complement activators, and risk of age-related macular degeneration, JAMA. 2006 Jul 19;296(3):301-9.DOI: 10.1001/jama.296.3.301
Lotery AJ, Baas D, Ridley C, Jones RP, Klaver CC, Stone E, Nakamura T, Luff A, Griffiths H, Wang T, Bergen AA, Trump D.Reduced secretion of fibulin 5 in age-related macular degeneration and cutis laxa,  Hum Mutat. 2006 Jun;27(6):568-74.DOI: 10.1002/humu.20344
2005

2005

van Leeuwen R, Boekhoorn S, Vingerling JR, Witteman JC, Klaver CC, Hofman A, de Jong PT.Dietary intake of antioxidants and risk of age-related macular degeneration, JAMA. 2005 Dec 28;294(24):3101-7.DOI: 10.1001/jama.294.24.3101
Ikram MK, van Leeuwen R, Vingerling JR, Hofman A, de Jong PT.Retinal vessel diameters and the risk of incident age-related macular disease: the Rotterdam Study, Ophthalmology. 2005 Apr;112(4):548-52.DOI: 10.1016/j.ophtha.2004.10.038
Skenduli-Bala E, de Voogd S, Wolfs RC, van Leeuwen R, Ikram MK, Jonas JB, Bakker D, Hofman A, de Jong PT.Causes of incident visual field loss in a general elderly population: the Rotterdam study, Arch Ophthalmol. 2005 Feb;123(2):233-8.DOI: 10.1001/archopht.123.2.233
Assink JJ, Klaver CC, Houwing-Duistermaat JJ, Wolfs RC, van Duijn CM, Hofman A, de Jong PT.Heterogeneity of the genetic risk in age-related macular disease: A population-based familial risk study, Ophthalmology. 2005 Mar;112(3):482-7.DOI: 10.1016/j.ophtha.2004.10.035
Hageman GS, Anderson DH, Johnson LV, Hancox LS, Taiber AJ, Hardisty LI, Hageman JL, Stockman HA, Borchardt JD, Gehrs KM, Smith RJ, Silvestri G, Russell SR, Klaver CC, Barbazetto I, Chang S, Yannuzzi LA, Barile GR, Merriam JC, Smith RT, Olsh AK, Bergeron J, Zernant J, Merriam JE, Gold B, Dean M, Allikmets R.A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration,  Proc Natl Acad Sci U S A. 2005 May 17;102(20):7227-32.DOI: 10.1073/pnas.0501536102
2004

2004

Tomany SC, Wang JJ, Van Leeuwen R, Klein R, Mitchell P, Vingerling JR, Klein BE, Smith W, De Jong PT.Risk factors for incident age-related macular degeneration: pooled findings from 3 continents, Ophthalmology. 2004 Jul;111(7):1280-7. DOI: 10.1016/j.ophtha.2003.11.010
van Leeuwen R, Klaver CC, Vingerling JR, Hofman A, van Duijn CM, Stricker BH, de Jong PT.Cholesterol and age-related macular degeneration: is there a link?, Am J Ophthalmol. 2004 Apr;137(4):750-2.DOI: 10.1016/j.ajo.2003.09.015
2003

2003

van Leeuwen R, Klaver CC, Vingerling JR, Hofman A, de Jong PT.The risk and natural course of age-related maculopathy: Follow-up at 6 1/2 years in the Rotterdam study, Arch Ophthalmol. 2003 Apr;121(4):519-26.DOI: 10.1001/archopht.121.4.519
Klaver CCW, Allikmets R.Genetics of macular dystrophies and implications for age-related macular degeneration, Dev Ophthalmol. 2003;37:155-69.DOI: 10.1159/000072045
Smith RT, Nagasaki T, Sparrow JR, Barbazetto I, Klaver CC, Chan JK.A method of drusen measurement based on the geometry of fundus reflectance, Biomed Eng Online. 2003 Apr 18;2:10.DOI: 10.1186/1475-925x-2-10
Van Leeuwen R, Klaver CCW, Vingerling JR, Hofman A, De Jong PTVM.Epidemiology of age-related maculopathy: A review, European Journal of Epidemiology. 2003;18(9):845-54.DOI: 10.1023/a:1025643303914
2002

2002

Hoyng CB, Tromp AI, Meulendijks CF, Leys A, van der Maazen RW, Deutman AF, Vingerling JR.Side effects after radiotherapy of age-related macular degeneration with the Nijmegen technique, Graefes Arch Clin Exp Ophthalmol. 2002 May;240(5):337-41.DOI: 10.1007/s00417-002-0428-4
Schmidt S, Klaver C, Saunders A, Postel E, De La Paz M, Agarwal A, Small K, Udar N, Ong J, Chalukya M, Nesburn A, Kenney C, Domurath R, Hogan M, Mah T, Conley Y, Ferrell R, Weeks D, de Jong PT, van Duijn C, Haines J, Pericak-Vance M, Gorin M.A pooled case-control study of the apolipoprotein E (APOE) gene in age-related maculopathy,  Ophthalmic Genetics. 2002;23(4):209-23.DOI: 10.1076/opge.23.4.209.13883
2001

2001

van Leeuwen R, Vingerling JR, de Jong PT.Risk of macular degeneration with statin use should be interpreted with caution,  BMJ. 2001 Dec 1;323(7324):1308.PMCID: PMC1121762
Klaver CC, Assink JJ, van Leeuwen R, Wolfs RC, Vingerling JR, Stijnen T, Hofman A, de Jong PT.Incidence and progression rates of age-related maculopathy: The Rotterdam Study,  Invest Ophthalmol Vis Sci. 2001 Sep;42(10):2237-41.http://iovs.arvojournals.org/article.aspx?articleid=2200031

Gorin MB, Breitner JC

De Jong PT, Hageman GS, Klaver C C, Kuehn MH, Seddon JM

 

The genetics of age-related macular degeneration, Molecular Vision. 1999;5:29.http://www.molvis.org/molvis/v5/a29/
Smith W, Assink J, Klein R, Mitchell P, Klaver CC, Klein BE, Hofman A, Jensen S, Wang JJ, de Jong PT.Risk factors for age-related macular degeneration: Pooled findings from three continents, Ophthalmology. 2001;108(4):697-704.DOI: 10.1016/s0161-6420(00)00580-7
1998

1998

Klaver CC, Wolfs RC, Vingerling JR, Hofman A, de Jong PT.Age-specific prevalence and causes of blindness and visual impairment in an older population: The Rotterdam study, Arch Ophthalmol. 1998 May;116(5):653-8.DOI: 10.1001/archopht.116.5.653
Klaver CC, Kliffen M, van Duijn CM, Hofman A, Cruts M, Grobbee DE, van Broeckhoven C, de Jong PT.Genetic association of apolipoprotein E with age-related macular degeneration, Am J Hum Genet. 1998 Jul;63(1):200-6.DOI: 10.1086/301901
1997

1997

Klaver CC, Assink JJ, Vingerling JR, Hofman A, de Jong PT.Smoking is also associated with age-related macular degeneration in persons aged 85 years and older: The Rotterdam Study, Arch Ophthalmol. 1997 Jul;115(7):945.DOI: 10.1001/archopht.1997.01100160115033
1996

1996

Vingerling JR, Hofman A, Grobbee DE, de Jong PT.Age-related macular degeneration and smoking. The Rotterdam Study, Arch Ophthalmol. 1996 Oct;114(10):1193-6.DOI: 10.1001/archopht.1996.01100140393005
Klaver CC, Wolfs RC, Vingerling JR, Hofman A, de Jong PT.Prevalence and causes of blindness in subjects of 55 years and older: The Rotterdam study, Arch Ophthalmol. 1998 May;116(5):653-8.DOI: 10.1001/archopht.116.5.653
1995

1995

Vingerling JR, Dielemans I, Bots ML, Hofman A, Grobbee DE, de Jong PT.Age-related macular degeneration is associated with atherosclerosis. The Rotterdam Study, Am J Epidemiol. 1995 Aug 15;142(4):404-9.DOI: 10.1093/oxfordjournals.aje.a117648
Vingerling JR, Dielemans I, Witteman JC, Hofman A, Grobbee DE, de Jong PT.Macular degeneration and early menopause: a case-control study, BMJ. 1995 Jun 17;310(6994):1570-1.DOI: 10.1136/bmj.310.6994.1570
Bird AC, Bressler NM, Bressler SB, Chisholm IH, Coscas G, Davis MD, De Jong PTVM, Klaver CCW, Klein BEK, Klein R, Mitchell P, Sarks JP, Sarks SH, Soubrane G, Taylor HR, Vingerling JRAn international classification and grading system for age-related maculopathy and age-related macular degeneration: The International ARM Epidemiological Study group, Surv Ophthalmol. 1995 Mar-Apr;39(5):367-74.DOI: 10.1016/s0039-6257(05)80092-x
Vingerling JR, Klaver CCW, Hofman A, De Jong PTVM.Epidemiology of age-related maculopathy, Epidemiologic Reviews. 1995;17(2):347-60.DOI: 10.1093/oxfordjournals.epirev.a036198
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